From Chapter 2:
smoking was not confined to the auditors on the stage, who paid sixpence each for a stool. There was the "lords' room" over the stage, which seems to have corresponded with the modern stage boxes, the price of admission to which appears to have been a shilling, where the pipe was also in full blast. Dekker tells how a gallant at a new play would take a place in the "twelve penny room, next the stage, because the lords and you may seem to be hail fellow, well met"; and Jonson, in "Every Man out of his Humour," 1600, speaks of one who pretended familiarity with courtiers, that he talked of them as if he had "taken tobacco with them over the stage, in the lords' room."

From Chapter 5:
The belief in the prophylactic power of tobacco was, however, very generally held. When Mr. Samuel Pepys on June 7, 1665, for the first time saw several houses marked with the ominous red cross, and the words "Lord, have mercy upon us" chalked upon the doors, he felt so ill at ease that he was obliged to buy some roll tobacco to smell and chew. There is nothing to show that Pepys even smoked, which considering his proficiency in the arts of good-fellowship, is perhaps a little surprising. Defoe, in his fictitious but graphic "Journal of the Plague Year in London," says that the sexton of one of the London parishes, who personally handled a large number of the victims, never had the distemper at all, but lived about twenty years after it, and was sexton of the parish to the time of his death. This man, according to Defoe, "never used any preservative against the infection other than holding garlic and rue in his mouth, and smoking tobacco."