From Chapter 1:
The truth probably is that whoever actually smoked the first pipe, it was Raleigh who brought the practice into common use. It is highly probable, also, that Raleigh was initiated in the art of smoking by Thomas Hariot. This was made clear, I think, by the late Dr. Brushfield in the second of the valuable papers on matters connected with the life and achievements of Sir Walter, which he contributed under the title of "Raleghana" to the "Transactions" of the Devonshire Association. Hariot was sent out by Raleigh for the specific purpose of inquiring into and reporting upon the natural productions of Virginia. He returned in 1586, and in 1588 published the results of his researches in a thin quarto with an extremely long-winded title beginning "A briefe and true report of the new found land of Virginia" and continuing for a further 138 words.

From Chapter 8:
All's well that ends well; but one cannot help wondering what kind of tobacco it was that the Birmingham tradesman used, a half pipeful of which had such a deadly effect—but perhaps the effect was due to the salt, not to the tobacco.
In the year after that which witnessed Coleridge's adventure, i.e. in 1796, a tobacco-box with a history was the subject of a legal decision. This box, made of common horn and small enough to be carried in the pocket, was bought for fourpence by an overseer of the poor in the time of Queen Anne, and was presented by him in 1713 to the Society of Past Overseers of the parish of St. Margaret, Westminster. In 1720 the Society, in memory of the donor, ornamented the lid with a silver rim; and at intervals thereafter additions were made to an extraordinary extent to the box and its casings. Hogarth engraved within the lid in 1746 a bust of the victor of Culloden. Gradually the horn box was enshrined within one case after another—usually silver lined with velvet—each case bearing inscribed plates commemorating persons or events. A Past Overseer who detained the box in 1793 had to give it back after three years of litigation. A case of octagon shape records the triumph of Justice, and Lord Chancellor Loughborough pronouncing his decree for the restitution of the box on March 5, 1796. In later days many and various additions have been made to the many coverings of the box, recording public events of interest.