From Chapter 1:
"'It requires no effort of the fancy to picture these three men [Shakespeare, Bacon and Raleigh] as lounging in a window of Durham House, puffing the new Indian weed from silver bowls, discussing the highest themes in poetry and science, while gazing on the flower-beds and the river, the darting barges of dame and cavalier, and the distant pavilions of Paris garden and the Globe.'" This is a pure "effort of the fancy" so far as Bacon and Shakespeare are concerned. Shakespeare's absolute silence about tobacco forbids us to assume that he smoked; but of Raleigh the picture may be true enough. The house had, as Aubrey tells us, "a little turret that looked into and over the Thames, and had the prospect which is as pleasant perhaps as any in the world"; and it would be strange indeed if the owner of the noble house did not often smoke a contemplative pipe in the window of that pleasant turret.

From Chapter 8:
In the whole sixteen volumes of Walpole's correspondence, as so admirably edited by Mrs. Toynbee, there is scarcely a mention of tobacco; and the same may be said of other collections of letters of the same period—the Selwyn letters, the Delany correspondence, and so on. Neither Walpole nor any member of the world in which he lived would appear to have smoked. In Miss Burney's "Evelina," 1778, from the beginning to the end of the book there is no mention whatever of tobacco or of smoking. Apparently the vulgar Branghtons were not vulgar enough to smoke. Such use of tobacco was considered low, and was confined to the classes of society indicated in the preceding chapter. One of the characters in Macklin's "Love à la Mode," 1760, is described as "dull, dull as an alderman, after six pounds of turtle, four bottles of port, and twelve pipes of tobacco."